�Low levels of LDL cholesterol as well as high levels are associated with cancer in patients with type 2 diabetes, found a prospective cohort study promulgated in CMAJ.
Researchers from the Hong Kong Institute of Diabetes and Obesity, the Li Ka Shing Institute of Health Sciences and The Chinese University of Hong Kong conducted a field of study of 6107 Chinese patients with type 2 diabetes and set up a V-shaped risk relation between LDL cholesterol and cancer in patients non receiving lipid-lowering medication therapy.
"LDL cholesterol levels below 2.80 mmol/L and levels of at least 3.90 mmol/L were both associated with markedly elevated risk of cancer among patients wHO did non use statins," state Dr. Juliana Chan and coauthors.
The study excluded people on statins as statins obscured the association between LDL cholesterin and all-site cancer.
Increasing data suggests an association between type 2 diabetes and an elevated endangerment of cancer, including breast, colorectal, pancreatic and liver cancers. An elevated risk of exposure of genus Cancer in patients with humbled LDL was linked to cancers of digestive organs and peritoneum, genital and urinary organs, lymphatic and blood tissues as well as other areas. Patients with an LDL cholesterin level supra 3.80 mmol/L had heightened risks of oral, digestive, bone, skin, connection tissue, breast and other cancers.
Regarding clinical implications, the authors suggest "the use of these levels as risk markers may help clinicians to evaluate their patients more in full and therefore to forestall premature deaths in patients who have high peril."
They bid for re-analysis of data from clinical trials to confirm or refute these findings.
In a related commentary, Drs. Frank Hu and Eric Ding of Harvard School of Public Health order confounding factors such as indication for the use of statins, lifestyle and socioeconomic status must be considered when looking at the tie-up of high levels of LDL cholesterol and the risk of cancer.
"Low serum cholesterin is usually observed in individuals with ill health (e.g. cancer patients) and those with unhealthy lifestyle characteristics such as smoking and heavy imbibing," states Hu.
About CMAJ (Canadian Medical Association Journal)
CMAJ is the leading health sciences journal in Canada. CMAJ is a general aesculapian journal publishing original research and revue articles, commentaries and editorials, practice updates, an humanistic discipline and ideas section and health news. Published continuously since 1911, new issues are uploaded on hypertext transfer protocol://www.cmaj.ca every second Monday at 4:30 p.m. EST/EDT. http://www.cmaj.ca contains the complete editorial contents of CMAJ, supplemented by a variety of interactive features and extra content.
Canadian Medical Association Journal
More info
Tuesday, 2 September 2008
Saturday, 23 August 2008
Amy MacDonald wants to team up with The Killers
Amy MacDonald has admitted that she would love to join forces with The Killers.
The Scottish singer, whose song 'Run' was divine by the Las Vegas four-piece as previously reported on NME.COM, recently stayed up all night to see the band play at the Lowlands festival in Holland.
Posting on her MySpace pageboy she aforesaid: "The Killers were amazing, as common. I felt so inspired watching them.
"My absolute aspiration in life would be to do something with The Killers. They are one of my deary bands.
"I think out of a lot of bands and artists around nowadays selfsame few will still be around in 20 years time. The Killers will definitely be one of them."
MacDonald besides admitted that she base singer Brandon Flowers "absolutely mesmorising as a performing artist".
Aug 23, 2008 at Richfield Avenue, Festival, Reading -
Aug 24, 2008 at Bramham Park, Leeds -
More information
The Scottish singer, whose song 'Run' was divine by the Las Vegas four-piece as previously reported on NME.COM, recently stayed up all night to see the band play at the Lowlands festival in Holland.
Posting on her MySpace pageboy she aforesaid: "The Killers were amazing, as common. I felt so inspired watching them.
"My absolute aspiration in life would be to do something with The Killers. They are one of my deary bands.
"I think out of a lot of bands and artists around nowadays selfsame few will still be around in 20 years time. The Killers will definitely be one of them."
MacDonald besides admitted that she base singer Brandon Flowers "absolutely mesmorising as a performing artist".
Aug 23, 2008 at Richfield Avenue, Festival, Reading -
Aug 24, 2008 at Bramham Park, Leeds -
More The Killers tickets
More information
Wednesday, 6 August 2008
Thursday, 26 June 2008
Trick Daddy Ft Baby
Artist: Trick Daddy Ft Baby
Genre(s):
Rap: Hip-Hop
Discography:
Tuck Ya Ice-(Promo CDS) Proper
Year: 2007
Tracks: 3
Lior
Wednesday, 18 June 2008
Foo Fighters - Led Zepplin Join Foo Fighters On Stage At Wembley
There had been rumours flying around for most of the last week and they proved true as members of Led Zepplin joined the Foo Fighters on stage for a surprise encore at the band's second night at Wembley stadium yesterday.
Guitarist Jimmy Page and bassist John Paul Jones teamed up with Dave Grohl and his band for Zeppelin classics Rock and Roll and Ramble On.
Singer Robert Plant was busy on solo duties in America but the occasion still marked the first appearnce of Led Zepplin since the band played a one-off gig in December 2007.
It also came eight months after Queen joined Foo Fighters onstage in London.
Introducing the pair onstage Grohl said: "Tonight playing here at Wembley Stadium is an honour and if we didn't take advantage of this opportunity we'd be crazy.
He went on: "We knew from the beginning this wasn't going to be another outdoor show, we have been planning this for six months so we would like to welcome Jimmy Page and John Paul Jones onstage."
Grohl swapped drumming duties with Taylor Hawkins who sang vocals on Rock And Roll for Zeppelin's first appearance since their London 02 Arena gig in December 2007.
Grohl then swapped places with Hawkins for a crowd pleasing rendition of Ramble On.
Earlier in the night Grohl hinted that the band had something special planned when he told the crowd: "We are going to do something special tonight that we have never done before.
"Tonight this will be the show we are talking about for the next 20 years."
It was clearly an emotional moment for Grohl who told his fans "Welcome to the greatest f**king day day of my life".
08/06/2008 11:59:12
See Also
Monday, 9 June 2008
H-Man
Artist: H-Man
Genre(s):
Electronic
Discography:
51 Poland Street (GIANT33) Vinyl
Year: 2006
Tracks: 3
Tuesday, 3 June 2008
Juno star drops out of Rami horror movie
Actress Ellen Page has pulled out of Sam Raimi's new horror movie 'Drag Me To Hell'.
The 'Juno' star had agreed to play the lead role in the film, however scheduling conflicts have now forced her to withdraw.
Shooting was due to get underway on March 17 in a bid to wrap before the possible Screen Actors Guild strike on June 30, but was then delayed.
However, the new date clashed with Page's forthcoming roles in psychological thriller 'Peacock' and Drew Barrymore's directorial debut 'Whip It!'
A statement from producers Ghost House Pictures and financier Mandate Pictures, read: "We were racing to start production so that we could accommodate Ellen's schedule.
"But like so many other productions trying to start before the potential SAG strike date, this one needed more time and we had to push back the start of production."
The 'Juno' star had agreed to play the lead role in the film, however scheduling conflicts have now forced her to withdraw.
Shooting was due to get underway on March 17 in a bid to wrap before the possible Screen Actors Guild strike on June 30, but was then delayed.
However, the new date clashed with Page's forthcoming roles in psychological thriller 'Peacock' and Drew Barrymore's directorial debut 'Whip It!'
A statement from producers Ghost House Pictures and financier Mandate Pictures, read: "We were racing to start production so that we could accommodate Ellen's schedule.
"But like so many other productions trying to start before the potential SAG strike date, this one needed more time and we had to push back the start of production."
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